• Missing Poster: Dying in a sacrifice room while holding this trinket will reveal a puzzle piece on the death screen. * item room, treasure room, item room pool, deathstar, death star, dice pip, white, circle, sphere. • Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick. • When you kill an enemy, you have a chance to spawn a transparent Dead Bird familiar. Allows Isaac to consume keys and fire them at enemies. • Isaac's tears are replaced with a laser that has unlimited range and can only fire at right angles. • Enemies and pickups (keys, bombs etc.) • When you die with this item, you respawn in the same room with 1 heart and the Anemic item. • Bob's Brain deals 60 damage and applies a poison damage over time effect, which will scale with damage upgrades. • The charge of the spacebar attack deals 40 damage on contact Multiple tears will form a trail of tears that drags behind Isaac as he moves, bursting and dealing damage upon contact with enemies. Allows angels rooms to be found even if the previous run included devil deals. * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange. syringe, needle, injection, purple, grey, gray. Item Pool: Devil Room, Curse Room, Red Chest, Gold Chest, * curse room pool, red chest pool, red chest item After a * item room, treasure room, item room pool, knuckle, dusters, four, silver, grey, gray. • Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time. • Has a small chance to drop from the Steven boss fight. remaining or less AND also removes her 0.75 damage multiplier, raising judgement pool, devil beggar pool devil pool, devil room pool, devil grey, gray, green, mouth. UNLOCK: Unlock this item by beating Challenge #16 (Computer Savvy). • Crushed rocks and poop can fill holes if you walk in their direction. the lost item pool, white, black. devil deal, pink, brown, face, spots. • Caves 1: 1 Boss Item. UNLOCK: Unlock this item by beating each of the Seven Sins once. • The Boomerang can be used to kill shopkeeper corpses, allowing you to farm their drops for coins, items, Steam Sale etc. * item room, treasure room, item room pool, poison, green, brown, bottle, jar, danger. * boss room pool, boss room item, sticks, brown, yellow, * angel room pool, god room pool, angel room item, the lost item pool, cup, wooden, gold, • Dying in a sacrifice room while holding this trinket will reveal a puzzle piece on the death screen. While he is alive, he receives bonus items from all sources. • Creates 5 beams of light from the sky that deal damage equal to Time is the essence", • "Sleeping gatekeepers will need to be awoken with a loud sound". • Upon use, any pedestal item (e.g. * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray. • A familiar that mirrors the player's movements and shoots tears directly at Isaac. UNLOCK: Unlock this card by beating Challenge 3x (Turbo!). consumables such as keys and bombs. In Afterbirth The Lost starts with this item after donating 879 coins to the Greed Donation Machine. • Does not work for soul hearts, nickels, dimes, cards or pills. pink, purple. • Gives you access to the Dark Room floor. pickups, including hearts, keys, bombs, coins, pills, cards or trinkets. • Affects the speed of all other orbitals, slowing them down a • BFFs will cause the Guillotine head to do double damage (14 damage per tick). Three years later, he found himself facing the same predicament but with an even greater plague of horrors and peril. * angel room pool, god room pool, angel room item, yellow, blue, red, triangle, all seeing eye. • Does not show the icons for any unknown rooms. In Afterbirth this item can cause enemies to drop black hearts if it was poisoned. • Each time an item is generated by the D4, it is also removed • If at full health, any Rotten Hearts picked up will replace the rightmost red heart. white, grey, gray. • Despite the very small tears visually, Proptosis is always a UNLOCK: Unlock this item by beating Boss Rush with The Lost. • Isaac now shoots from both eyes at the same time. • Temporarily makes Isaac huge, giving him +7 Damage Up and +30 Range Up for the rest of the current room, • Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Coper140, *, mtg, card, magic, gathering, green, brown, • Spawns 3 random cards on the floor when used, • When used, this card will slow down enemies and Isaac's tears, but speed up Isaac's movement speed for the rest of the current room, • 48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. • When used, farts on nearby enemies and knocks them backwards away from Isaac. * , the lost item pool, tong, red, bloody, lips. • Allows Mom's Wig to spawn a maximum of 10 spiders at once instead of 5. shop room pool, shop item pool, cross, brown. Syncer 88,839 views * item room, treasure room, item room pool, brown, glass, beaker, white, * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, • A familiar that is controlled via the arrow keys and will automatically fire a laser if anything is in its line of sight. UNLOCK: Unlock this item by defeating Delirium in The Void floor with The Lost. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, • When used, turns every normal enemy in the room into poop! overall. UNLOCK: Unlock this item by beating all bosses and completing all post-it note marks in hard mode with The Lost character. When Isaac’s mother starts hearing the voice of God demanding a sacrifice be made to prove her faith, Isaac escapes into the basement facing droves of deranged enemies, lost brothers and sisters, his fears, and eventually his mother. normal beggar pool, normal judgement pool, coin beggar pool, coin UNLOCK: Unlock this card by beating Challenge #8 (Cat Got Your Tongue). • Reveals the locations of the secret and super secret room for the current floor and all future floors. Displays a random fortune, and has a chance to drop a soul heart, card, rune or trinket. • Guaranteed Devil or Angel Room if you have it when you kill the boss on all floors where it's possible to get one. • If Isaac is damaged while the effect is active, it will deactivate. lot (NOTE: This effect does not happen until you get a new orbital after judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, • Upon use, this item consumes 1 heart container or 2 soul hearts and spawns one item pedestal from the current room's pool, • The removed health container turns into a broken heart, meaning that slot is permanently broken and the maximum health limit is reduced by 1 for the rest of the run, • After 12 uses, Isaac dies instantly (this also applies to The Lost despite having no health), • Picking up Magic Skin and discarding it for another active item will give it a 100% chance to appear again on your next item pedestal found, • Magic Skin will continue to appear after finding it once if you are not still holding it - the chance for it to replace an item is 1 ÷ (12 - number of times used) up to a maximum of 50%. • Feared enemies will run away from Isaac temporarily. Close Send. • The chance to fire a tooth is affected by your luck stat and at +9 Luck it will activate every time. 18 new items, including a few which were planned for the initial release but didn’t make it in time; 8 new enemies, 2 new bosses and a few tweaks to existing ones to make them fairer; All of the 5 missing challenges will be playable; On top of that, many synergies have been added, some of … ), • Gives -1 tear delay (tears up) for each room completed without taking damage, up to a maximum of -6, • When you take damage, all stat upgrades given by this item are reset, • This item is recharged 1 bar for each tear fired, • At the beginning of each new floor, this item will stab Isaac and reduce your red health down to half a heart, but give a damage and speed up, • If Isaac is already at half a red heart when stabbed, no damage or speed increases are given, • The damage from being stabbed can be avoided with invincibility, however no damage or speed stat increases are gained if you do, • Your individual tears each gain a random effect (e.g. Comment. - Speeds up all enemies for the rest of the room. • Black Candle removes the teleportation effect of Cursed Eye, and the Curse of the Tower's bomb spawning effect. • Spiders are spawned at the location where the enemy died. ), • Resets all of your stats back to their original values, • Prevents stats from being reduced any more for the rest of the run. They also deal contact damage to enemies caught in them. • Aiming in the opposite direction is often better due to how the tears circle around Isaac. • Does not appear to affect your damage and only the hitbox size of tears. • If thrown at a multi-phase boss that works from a single health bar such as Isaac, ??? • Increases your chances to find an Angel Room instead of a Devil Room. • Isaac's health is set to 1 and he also gains 9 extra lives. paper, roll, white. • Each laser does damage equal to your current tear damage. • Isaac's tears now split into two upon contact with enemies or the environment. The official subreddit for Edmund McMillen's Zelda-inspired roguelike, The Binding of Isaac! • Gives a 25% chance to reveal map icons at the start of a new floor (The same effect as the Compass). UNLOCK: Unlock this item by destroying 100 tinted rocks. • This is completely useless if you currently have both the Treasure Map and The Compass. *, the lost item pool, tarot, card, blue, red. it up to 1.0. Grants 5 bombs. • An item that can be found in the Angel room. beggar pool, coin judgement pool, secret room pool, item room, treasure UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss. Item Pool: None (Blood Donation machine only). Most of them are identical to the originals, except a few ones which I will talk about below. If the small orbitals take enough damage, they burst into a few blue spiders, and the large orbital respawns. * secret room pool, shop room pool, shop item pool, item room, treasure room, item room pool, • When taken with another item which gives an extreme value in a certain stat (e.g. UNLOCK: Unlock this item by donating 400 pennies to the Shop. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, UNLOCK: Unlock this card by beating Challenge #10 (Cursed!). • Gives Isaac a higher chance to find pills. pool, devil room pool, devil deal, item room, treasure room, item room Edit: December 2016 - Got some sweet Antibirth seeds? If you aim well, you have double damage. pool, , dungeon room, blood challenge room, arena pool, shop room pool, * tinted rock, marked rock, grey, gray, lump, white. • Allows you to store up a lot of tears in the air and release them all at once. apply a Damage over Time effect that does 4 or 6 damage per tick. UNLOCK: Unlock this item by defeating The Witness as with every character on Hard Mode. • Has a very small chance to drop after destroying one of the pots that appear in the Basement and Cellar floors. • Creates friendly attack spiders when Isaac is damaged. • Upon use, re-rolls all pickup consumables in the current room into another random kind of pickup. • Isaac's touch now petrifies enemies, turning them to gold for a few seconds. • When used, freezes all enemies in the current room temporarily. • Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick. Grants different effects depending on which character you're playing as. • An item that often appears in the shop. The latest expansion to The Binding of Isaac: Rebirth features: – 55+ new items UNLOCK: Unlock this item by beating Boss Rush with Blue Baby. * item room, treasure room, item room pool, baby, pink. Maybe it's not Rebirth or Afterbirth, but it's still fun! * shop room pool, shop item pool, red, croissant, crescent. * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, • Gives Isaac angel wings for the current room, allowing him to fly. • When you hit a speed stat of 2.0, Isaac will gain the My Little • Can be used to go in and out of a Curse Room without taking damage. the lost item pool. This essentially means you are sacrificing your heart drops for a higher chance of • When you get hit, you will sometimes cause hearts to drop on the floor. • Tears shrink and grow in size as they go across the room. • Gives Isaac a higher chance to find Tarot cards after clearing a room or from chests. • When used, places a sword directly above Isaac's head and while active will spawn an extra item for every item pedestal spawned. your tear damage + 20 to any enemies which come into contact with them. * secret room pool, mondrian, painting, yellow, blue, red, white. UNLOCK: Unlock this item by beating Mom's Heart 6 times. • Allows you to crush Red Poops and sometimes not take damage. beggar pool, secret room pool, devil pool, devil room pool, devil deal,